AAP/AAPD 2019 · ACEP

Pediatric Procedural Sedation: Ketamine, Intranasal Fentanyl & Midazolam

Pick the procedure. Doses are calculated for the weight entered. Tap any earlier answer to change it.

Tap one answer per step. The plan appears when the last step is answered.
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kg Optional — enter kg to see doses in mg.

About this tool

This tool helps emergency and acute care clinicians choose a sedation or analgesia approach for children having procedures. It suggests agents by procedure type and calculates weight-based doses.

You pick the procedure: a painful procedure such as fracture reduction or abscess drainage, a simple laceration or IV in an anxious child, non-painful imaging such as CT or MRI, or anxiety before a minor procedure. The tool then checks for higher-risk features: ASA class III or higher, an abnormal airway, age under 3 months or former preterm under 60 weeks postmenstrual age, or active respiratory infection with wheeze or stridor. Any of these points to involving anesthesia or a sedation team.

Painful procedures get ketamine IV 1–1.5 mg/kg or IM 4–5 mg/kg, with intranasal fentanyl 1.5 mcg/kg for early analgesia. Lacerations get LET gel with intranasal midazolam or nitrous oxide. Imaging gets intranasal dexmedetomidine 2–3 mcg/kg or oral midazolam. Each result lists fasting times, monitoring, airway equipment, discharge criteria and reversal agents (naloxone, flumazenil). It draws on the AAP/AAPD 2019 sedation guideline, the 2011 ketamine guideline (Green et al.) and the 2014 ACEP clinical policy.

Common questions

What is the ketamine dose for pediatric procedural sedation?

For painful procedures the tool gives ketamine IV 1–1.5 mg/kg over 30–60 seconds, repeating 0.5–1 mg/kg if needed, or IM 4–5 mg/kg if there is no IV. Ketamine is avoided under 3 months.

What is the intranasal fentanyl dose for children?

Intranasal fentanyl 1.5 mcg/kg (max 100 mcg), given by atomizer and split between nostrils. It may be repeated at 0.5–1 mcg/kg.

What are the fasting times before pediatric sedation?

Clear fluids 2 hours, breast milk 4 hours, and formula or a light meal 6 hours. In the emergency department, recent intake is not an absolute barrier to ketamine or nitrous oxide, and urgency should be weighed.

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