Choose the exposure and get the right vaccine, immune globulin or antibiotic, with timing and exclusion rules.
This tool walks a clinician through post-exposure prophylaxis for a child after a common infectious exposure. The first question asks what the child was exposed to; the next one or two questions ask about immunity, age or risk group, and the tool then shows what to give, how soon, and at what dose.
It covers varicella (vaccine within 3–5 days or VariZIG within 10 days for high-risk groups), measles (MMR within 72 hours or immune globulin within 6 days), pertussis (azithromycin for all close contacts), meningococcal disease and Hib (rifampin, ceftriaxone, ciprofloxacin or azithromycin), hepatitis A, hepatitis B by vaccine and source status, and HIV nonoccupational PEP. Tetanus and rabies are handled in the wounds and bites tool.
Doses are per kilogram with a maximum per dose; enter a weight to see the calculated amount. Each result also lists isolation and return-to-school or child-care rules from the Red Book. Prophylaxis decisions for outbreaks, drug-resistant strains and HIV regimens should be made with the health department or an infectious diseases specialist.
MMR within 72 hours of exposure for children 6 months or older, or immune globulin within 6 days. Infants under 6 months get IGIM 0.5 mL/kg (max 15 mL); severely immunocompromised children and pregnant adolescents get IGIV 400 mg/kg whatever their vaccine history.
High-risk people without immunity: immunocompromised children, newborns whose mothers' varicella began 5 days before to 2 days after delivery, certain hospitalized preterm infants, and pregnant adolescents. Give it as soon as possible, up to 10 days after exposure.
Yes. Azithromycin is recommended for all household and close contacts regardless of age or vaccine status, within 21 days of the case's cough onset. Infants under 6 months get 10 mg/kg daily for 5 days.
Where ciprofloxacin-resistant strains have been reported. CDC advises switching to rifampin, ceftriaxone or azithromycin when there are 2 or more resistant cases making up at least 20% of cases in a 12-month period.
When all lesions have crusted. A vaccinated child with mild disease and no crusts can return once no new lesions appear for 24 hours.
Free to use on clinic, school, blog or hospital pages. Copy this code into your page: