Pedemy All toolsPick the problem and get the CDC regimen, follow-up testing and partner plan for an adolescent.
This tool gives the next steps for an adolescent with a sexually transmitted infection, a positive test, symptoms, or an exposure. It follows the CDC STI Treatment Guidelines 2021 and later CDC updates, as summarized in the AAP Red Book 2024–2027.
Most doses are fixed adult doses that apply to adolescents who weigh 45 kg or more. The gonorrhea pathway shows the higher ceftriaxone dose for 150 kg or more and the weight-based dose for smaller patients. Each result lists the follow-up test, the retest at 3 months, partner treatment and HIV and syphilis screening.
Prevention results cover HIV PrEP, nonoccupational HIV PEP within 72 hours and doxycycline PEP for eligible patients. An STI in a prepubertal child is flagged as possible sexual abuse that needs a report and a child abuse team; the tool does not manage that evaluation.
Doxycycline 100 mg twice daily for 7 days. Azithromycin 1 g once is used in pregnancy or when a 7-day course is unlikely to be completed. Retest in 3 months.
500 mg IM once for patients under 150 kg and 1 g for 150 kg or more. Add doxycycline if chlamydia has not been excluded. Pharyngeal gonorrhea needs a test of cure 7–14 days later.
Not because of age. Admit for pregnancy, tubo-ovarian abscess, a possible surgical emergency, severe illness or vomiting, inability to follow an oral plan, or no improvement after 72 hours.
Primary, secondary and early latent: benzathine penicillin G 2.4 million units IM once. Late latent or unknown duration: the same dose weekly for 3 weeks. Neurosyphilis, ocular or otic syphilis: IV aqueous penicillin G for 10–14 days.
Men who have sex with men and transgender women with a bacterial STI in the past 12 months. The dose is doxycycline 200 mg once within 72 hours after sex without a condom.
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